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pentobarbital will lessen the level or result of tamoxifen by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.pentobarbital will lessen the extent or outcome of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with potent CYP3A4 inducers is not really encouragedpentobarbital wi